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Genetically Encoded Azulenylalanine Reveals Vibrational Energy Transfer in Proteins

Professor Ned Budisa and Prof. Jens Bredenbeck from Goethe University in Frankfurt, Germany join their efforts to provide experimental evidence for vibrational energy transfer (VET) in proteins between allosterically communicating sites. In the last decade, considerable efforts have been made to understand the biophysical foundations of allostery, a ubiquitous phenomenon in functional proteins. While in computer simulations, mapping...


Seeing electrons: from individual atoms to processes inside cells

SOURCE: WIKIPEDIA: STRUCTURE OF ALCOHOL OXIDASE FROM PICHIA PASTORIS BY CRYO ELECTRON MICROSCOPY DECEMBER 1, 2017 — As part of the Faculty of Science Interdisciplinary Series, Unter to Uber, Dr. Lena F. Kourkoutis will be giving a special lecture on how new technology has made it possible to “see” inside molecules, even at the atomic level. Such...


cryo EM Seminar: Dr. Wayne Hendrickson, Violin Family Professor of Physiology and Cellular Biophysics, Columbia University

PHOTO CREDIT: KIRA KOOP JANUARY 23, 2018 —  HENDRICKSON, WAYNE A., PH.D. UNIVERSITY PROFESSOR AND THE VIOLIN FAMILY PROFESSOR OF PHYSIOLOGY AND CELLULAR BIOPHYSICS Dr. Wayne Hendrickson, the Violin Family Professor of Physiology and Cellular Biophysics and Professor, Department of Biochemistry and Molecular Biophysics at Columbia University will deliver a seminar on technological advances in cryo...


Professor Hélène Perreault, recognized for outstanding work in mass spectrometry

Meet Dr. Hélène Perreault, recognized as a leader among her peers in the field of mass spectrometry. Her main field of interest is to study glycosylated proteins, which are proteins that have naturally attached sugars. These sugars can change the function of a protein completely, and their presence or lack thereof can indicate or even...


Puzzling it out: solving the mysteries of molecules, one spectrum at a time

PHOTO CREDIT: KIRA KOOP. FEBRUARY 13, 2018 — Asked what it is about her specialty (microwave and infrared spectroscopy) that she finds so appealing, UofM Chemistry Professor Jennifer van Wijngaarden thinks for a moment before answering: “I like that it’s essentially a puzzle, and you’re finding the best solution. There’s never a perfect one. You’re just constantly...