Research and Teaching Interests
Our main focus is on better understanding the cellular mechanisms regulating cell migration and trafficking. We leverage microfluidic devices in combination with cell biology, immunology and modeling approaches in our studies. In addition, we are developing microfluidic tools for a range of biological and biomedical applications through collaborations.
Research Involves:
The study of environmental guiding mechanisms for the migration of biological cells with the focus on chemical and electrical cues.
Research Expertise:
biophysics, biomedical engineering, immunology, microfluidics, cell migration and cell trafficking
Research Highlight:
Microfluidic devices to study electrochemical guidance for cell migration and trafficking.
Publications:
- D. Wu, M.L. Dong, C. Rigatto, Y. Liu and F. Lin, “Lab-on-chip technology for chronic disease diagnosis”, npj Digital Medicine, 2018, DOI: 10.1038/s41746-017-0014-0.
- Yang, H. Peretz-Soroka, J.D. Wu, L. Zhu, X.L. Cui, M. Zhang, C. Rigatto, Y. Liu and F. Lin, “Fibroblast growth factor 23 weakens chemotaxis of human blood neutrophils in microfluidic devices”,Scientific Reports, 2017, 7: 3100, DOI: 10.1038/s41598-017-03210-0.
- D. Wu, C. Hillier, P. Komenda, R. Lobato de Faria, S. Santos, D. Levin, M. Zhang and F. Lin, “An all-on-chip method for testing neutrophil chemotaxis induced by fMLP and COPD patient’s sputum”, Technology, 2016, 4(2), 104-9.